Kinome expression profiling improves risk stratification and therapeutic targeting in myelodysplastic syndromes

作者：C. Yao, Chien-Chin Lin, Yu-Hung Wang, C. Kao, Xavier Cheng-Hong Tsai, H. Hou, H. Tien, Chia-Lang Hsu, W. Chou · 发表于：Blood Advances · 年份：2024 · DOI：10.1182/bloodadvances.2023011512 · 被引用次数：8 · 研究领域：Medicine

Key Points • Through transcriptomic analysis, we identified 7 kinases whose expressions were strongly predictive of compromised survival in MDS.• The KISS could improve risk stratification and imply novel therapeutic opportunities in MDS.