Clinical Observation of Silk Fibroin Dressing for Wound Healing after CO2 Fractional Laser Treatment

作者：Xia Zheyi, Zhou Qiwen, Chen Bo, Zhang Shuai · 发表于：Journal of Medicine and Health Science · 年份：2026 · DOI：10.62517/jmhs.202605218

To observe the clinical effect of silk fibroin dressing on wound healing and adverse reactions after CO2 fractional laser treatment. A total of 72 patients were randomly divided into an observation group (n=36) and a control group (n=36). Both groups received CO2 fractional laser therapy. After the surgery, the observation group used silk fibroin dressing (Fuxiang Sitai Medical Technology), and the control group used traditional ice compress. The results showed that at 30 minutes after treatment, the pain score (3.77 ± 0.78 vs 8.32 ± 0.57), burning score (1.67 ± 0.25 vs 2.89 ± 0.31), and redness and swelling score (1.74 ± 0.28 vs 2.43 ± 0.35) in the observation group were significantly lower than those in the control group (P < 0.05). At the same time, the scab formation time (1.93 ± 0.52 days vs 2.37 ± 0.48 days) and scab shedding time (6.74 ± 1.36 days vs 8.52 ± 1.41 days) in the observation group were significantly shorter (P < 0.05). At 28 days after treatment, the VISIA skin analysis showed that the percentile scores of erythema, texture, and brown spots in the observation group were significantly higher than the control group (P < 0.05), but there was no significant difference in porphyrins and pores (P > 0.05). In conclusion, the application of silk fibroin dressing after CO2 fractional laser can effectively reduce acute pain and inflammation, speed up skin healing, and repair the skin barrier.