Application of quantitative light-induced fluorescence technology in early caries detection and resin infiltration treatment.

作者：Yangyang Shi, Xue Feng, Mingyun Li, Xiao Guo, Haohao Wang, Dongyue Dai, Jinzhi He, Lei Cheng · 发表于：E -journal of dentistry · 年份：2025 · DOI：10.1016/j.jdent.2025.106086 · 研究领域：Medicine

OBJECTIVES The aim of this study is to explore the specific application scenarios of quantitative light-induced fluorescence (QLF) in the detection and treatment of early caries, so as to provide more evidence for the clinical application of QLF. METHODS (1) The accuracy of QLF in detecting the lesion depth of early caries was evaluated by combining transverse microradiography (TMR) and spectrophotometer analysis (n=6). (2) Resin infiltration therapy was used as a representative method for the treatment of early caries to evaluate the ability of QLF in assessing the therapeutic effect on early caries (n=6). (3) Re-demineralization of early caries after treatment was performed to evaluate the detection capability of QLF for deeper lesions (n=6). RESULTS In the detection of early caries, when the demineralization depth < 200 µm, both QLF and spectrophotometer analysis were accurate and correlated well with TMR results (r=-0.9938, r=-0.9534, p < 0.05). In addition, both QLF and spectrophotometer detection could effectively reflect the therapeutic effect on early caries after resin infiltration treatment. However, when the early caries treated with infiltrative resin were re-demineralized and the lesion depth > 200 µm, the diagnostic accuracy of QLF for the re-demineralized early caries decreased significantly, which was not as precise as TMR and spectrophotometer analysis. CONCLUSION When the demineralization depth is less than 200 µm, QLF can be used to detect early carie...