Reliability and Validity of the Serbian Version of the Hidradenitis Suppurativa Quality of Life Questionnaire (HSQoL-24)

作者：M. Marinković, M. Stojičić, Marko Jović, J. Rakočević, Z. Bukumirić, Milana Jurišić, Milan Jovanović, Jelena Jeremić, A. Vlahović, I. Vujcic, Nataša Maksimović · 发表于：Journal of Clinical Medicine · 年份：2026 · DOI：10.3390/jcm15062436 · 被引用次数：1 · 研究领域：Medicine

Background: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease characterized by painful nodules, abscesses, and sinus tracts in apocrine gland-rich areas, leading to significant impairment in patients’ quality of life (QoL). Persistent symptoms affect physical functioning, psychological well-being, social interactions, and intimate relationships. Therefore, validated disease-specific instruments are essential for accurate QoL assessment in different populations. Objective: The aim of this study was to validate the Serbian version of the Hidradenitis Suppurativa Quality of Life Questionnaire (HSQoL-24). Methods: The validation process followed established methodological guidelines for psychometric evaluation. The Serbian HSQoL-24 version demonstrated satisfactory psychometric properties. Internal consistency was excellent, with a Cronbach α of 0.907. Test–retest reliability was confirmed using an intraclass correlation coefficient (ICC) of 0.986 for the total score, demonstrating satisfactory reproducibility over time. A strong positive correlation was observed between the HSQoL-24 and Dermatology Life Quality Index (DLQI) total scores (Spearman’s ρ = 0.806, p < 0.001), confirming good convergent validity, particularly in domains related to symptoms and feelings, occupational or educational functioning, and interpersonal relationships. Moreover, total HSQoL-24 scores increased significantly with disease severity, indicating the questionnaire’s ability to disc...