Cannabis sativa L. biomass valorization as a strategic bioresource for South Africa’s circular bioeconomy: integrating biorefinery pathways and green extraction

作者：Lucia Motsa, N. Seedat, L. Mekuto, P. Sekoai · 发表于：Biomass Conversion and Biorefinery · 年份：2026 · DOI：10.1007/s13399-026-07177-9

South Africa’s legalized Cannabis Sativa L. industry generates substantial biomass waste, including post-harvest materials such as stalks, leaves, roots, and seeds, as well as post-extraction residues rich in lignocellulosic components (cellulose, lignin, hemicellulose) and functional compounds (fibers, phenolic compounds, and proteins) which remain largely unvalorized. This review critically and systematically examines valorization pathways for Cannabis sativa L. biomass within the context of a circular bioeconomy, focusing on its potential as a bioresource amid South Africa’s evolving regulatory, agricultural, and industrial landscape. A systematic scoping review of 65 peer-reviewed studies (2018–2025) was conducted using international databases to evaluate biochemical and thermochemical conversion, integrated biorefinery strategies, and green extraction methods such as supercritical CO2 extraction, microwave-assisted extraction (MAE), and ultrasound-assisted extraction (UAE). Compositional analysis indicates that lignocellulosic fractions from Cannabis sativa L., particularly bast fibers and hurds, are well-suited to cascaded biorefinery applications, enabling the recovery of cannabinoids, carbon-based materials, and bioenergy. However, several challenges persist, including biomass recalcitrance to enzymatic hydrolysis, inconsistent feedstock availability, and the lack of a standardized protocol within South Africa’s regulated environment. Techno-economic assessments (TEA)...