General and abdominal adiposity and hypertension in eight world regions: a pooled analysis of 837 population-based studies with 7·5 million participants

作者：Bin James E Aidan P Rosie K Anu Rodrigo M Nayu Lakshya Zhou Bennett Wickham Singleton Mishra Carrillo-Lar, Bin James E Aidan P Rosie K Anu Rodrigo M Nayu Lakshya Zhou Bennett Wickham Singleton Mishra Carrillo-Lar, Bin Zhou, James E. Bennett, Aidan P. Wickham, Rosie K. Singleton, Anu Mishra, R. Carrillo-Larco, Nayu Ikeda, Lakshya Jain, A. Barradas-Pires, Rachel A. Heap, Victor P. F. Lhoste, Kate E. Sheffer, N. H. Phelps, Archie W. Rayner, Edward W. Gregg, Mark Woodward, Gretchen A. Stevens, M. L. Iurilli, G. Danaei, M. di Cesare, Carlos A. Aguilar-Salinas, N. Ahmad, P. Bovet, Zhengming Chen, Albertino Damasceno, Sarah L. Filippi, I. Janszky, A. Kengne, Y. Khang, K. Khunti, A. Laxmaiah, Lee-Ling Lim, L. Lissner, P. Margozzini, J. Mbanya, S. McGarvey, Jonathan E. Shaw, S. Söderberg, Luis Adrián Soto-Mota, Jun-Yan Wang, F. Zaccardi, Majid Ezzati, Leandra Mohsen Shynar Suhaila Abdul Hanan F Abdul Zulfiya Abarca-Gómez Abbasi-Kangevari Abdrakhmanova Ghaffa, Leandra Abarca-Gómez, M. Abbasi-Kangevari, Shynar Abdrakhmanova, Suhaila Abdul Ghaffar, H. A. Abdul Rahim, Zulfiya Abdurrahmonova, N. Abu-Rmeileh, Benjamín Acosta-Cázares, Ishag Adam, Marzena Adamczyk, W. Aekplakorn, I. Agdeppa, J. Aghazadeh-Attari, C. Agyemang, Mohamad Hasnan Ahmad, Ali Ahmadi, Naser Ahmadi, N. Ahmadi, Soheir H. Ahmed, W. Ahrens, G. Aitmurzaeva, K. Ajlouni, H. Al-Hazzaa, Halima Al-Hinai, J. Al-Lawati, R. Al-Raddadi, Deena Al Asfoor, Huda M. Al Hourani, M. Alarouj, F. AlBuhairan, Shahla Aldhukair, M. M. Ali, Anna V. Alieva, Abdullah Alkandari, B. Alkhatib, Eman Aly, D. Amarapurkar, Pilar Amiano Etxezarreta, Norbert Amougou, Lars Bo Andersen, S. Anderssen, O. Androutsos, R. Anjana, A. Ansari-Moghaddam, E. Anufrieva, H. Aounallah-Skhiri, T. Aris, R. Arku, N. Arlappa, K. Aryal, Felix K. Assah, B. Assembekov, M. C. Assunção, J. Auvinen, M. Avdičová, Kishwar Azad, A. Azevêdo, Mohsen Azimi-nezhad, Fereidoun Azizi, Flora Bacopoulou, S. Bahijri, Izet Bajramović, Nagalla Balakrishna, M. Bamoshmoosh, Maciej Banach, P. Bandosz, J. Banegas, Rafał Baran, C. Barbagallo, Valter Barbosa, Alberto Barcelo, Maja Baretić, Joaquin Barnoya, Lena Barrera, Aluísio J. D. Barros, M. V. G. Barros, Abdul Basit, J. L. Bastos, A. Batieha, Aline P. Batista, R. Batista, Z. Battakova, L. Baur, P. Bayauli, S. Bel-Serrat, A. Belavendra, H. Ben Romdhane, T. Benedek, J. Benedics, M. Benet, Gilda Estela Benitez Rolandi, Michaela Benzeval, E. Bere, Nicolas Berger, I. Bergh, S. Berkinbayev, A. Bernabé-Ortiz, Heloísa Bettiol, Augustin F. Beybey, Jorge Bezerra, A. Bhagyalaxmi, Santosh K. Bhargava, Elysée Claude Bika Lele, M. Bikbov, B. Bista, D. Bjelica, Peter Bjerregaard, E. Bjertness, M. B. Bjertness, C. Björkelund, K. V. Bloch, A. Blokstra, Simona Bo, M. Bobak, L. Boddy, Bernhard O. Boehm, J. Boggia, Elena A. Bogova, M. Bonaccio, Alice Bonilla-Vargas, H. Borghs, S. Botomba, Rupert R. A. Bourne, K. Boymatova, Lutgart Braeckman, T. Braithwaite, I. Brajkovich, Francesco Branca, H. Brenner, L. Brewster, Y. Briceño, L. Brîndușe, B. Bringolf-Isler, Miguel Brito, Johannes Brug, A. Bugge, Frank Buntinx, M. Buoncristiano, Con Burns, A. D. de León, R. B. Caixeta, Tilema Cama, G. Can, A. P. Cândido, F. Cañete, M. Capanzana, N. Capkova, E. Capuano, R. Capuano, V. Capuano, V. C. Cardoso, Axel C. Carlsson, F. Casanueva, M. Casas, L. Censi, Marvin Cervantes-Loaiza, P. Chamnan, S. Chamukuttan, Queenie Chan, Nishi Chaturvedi, Fangfang Chen, Huashuai Chen, Long-Sheng Chen, Yi-Ling J. Cheng, Bahman Cheraghian, A. Chetrit, E. Chikova-Iscener, Mai Jm Chinapaw, A. Chinnock, A. Chiolero, A. Chiriță-Emandi, M. Chirlaque, C. Chong, D. Christofaro, Jerzy Chudek, R. Cífková, Massimo Cirillo, F. Claessens, Philip Clare, E. Cohen, S. C. Confortin, Tara C. Coppinger, L. Cortés, Cojocaru R. Cosmin, S. Costanzo, M. Cowan, Chris Cowell, A. Crampin, Amanda J. Cross, A. Crujeiras, Juan J. Cruz, Alexandra M. Cucu, F. Cureau, S. Cuschieri, Graziella D'Arrigo, Eleonora d'Orsi, Haroldo da Silva-Ferreira, C. Dahm, J. Dallongeville, R. Dankner, K. Davletov, F. de Assis Guedes de Vasconcelos, M. A. D. de Assis, D. de Bacquer, Jaco De Bacquer, J. de Bont, A. De Curtis, Patrícia Fragas Hinnig, G. de Gaetano, S. de Henauw, P. De Miguel-Etayo, P. D. de Oliveira, Karina Mary de Paiva, K. de Ridder, M. A. de Valois Correia, M. Deepa, V. Degennaro, S. Demarest, Elaine Dennison, Valérie Deschamps, M. Dhimal, María Pilar Díez Ripollés, Ž. Dika, S. Djalalinia, Liria Dominguez, M. Donati, C. Donfrancesco, Guanghui Dong, Silvana P. Donoso, M. Dorobanțu, M. Dörr, N. Dragano, W. Drygas, Shu-Fa Du, C. Duante, P. Duboz, Rosemary B. Duda, V. Duleva, A. Dushpanova, A. Dyussupova, E. Dziankowska-Zaborszczyk, Narges Ebrahimi, Guadalupe Echeverría, Ricky Eddie, E. Eftekhar, Vasiliki Efthymiou, E. Egbagbe, S. Eghtesad, U. Ekelund, Mohammad El-Khateeb, J. El Ati, R. Elosua, O. Enang, R. Erasmus, C. Erem, G. Ergor, L. Eriksen, J. Eriksson, Jorge Escobedo-de la Peña, A. Esmaeili, Roger G. Evans, I. Fakhradiyev, A. Fakhretdinova, Caroline H. D. Fall, E. Faramarzi, Mojtaba Farjam, F. Farzadfar, Y. Farzi, Mohammad-Reza Fattahi, Prof. Dr. Asher. Fawwad, F. Félix-Redondo, Trevor S. Ferguson, Romulo A. Fernandes, D. Fernández-Bergés, D. Fernando, Daniel Ferrante, Gerson Ferrari, M. Ferrari, C. Ferreccio, Eldridge B. Ferrer, Thamara Hübler Figueiró, Anna Fijałkowska, Günther Fink María Pilar, M. Fisberg, M. Forsner, E. Fottrell, Heba M. Fouad, Damian K. Francis, G. Frontera, F. Fuchs, Sandra C. Fuchs, Viktoriya Furdela, Takuro Furusawa, Stefan Adela Gabriela, Zbigniew A. Gaciong, Manuel Galán Cuesta, A. Galbarczyk, S. Galcheva, M. Galfo, M. García-de-la-Hera, Pablo M. Garcia, S. Garnett, Magda Gasull, A. Gazzinelli, Ulrike Gehring, E. Gerdts, E. Ghaderi, S. Ghamari, A. Ghanbari, E. Ghasemi, O. Gheorghe-Fronea, Anup Ghimire, A. Gialluisi, Simona Giampaoli, F. Gianfagna, G. Gironella, A. Giwercman, K. Gkiouras, N. Glushkova, Ramesh Godara, J. Godos, Marcel Goldberg, G. Gómez, Jesús Gómez, L. Gómez, Santiago F. Gómez, Aleksandra Gomuła, Bruna Gonçalves Cordeiro da Silva, H. Gonçalves, Mauer Gonçalves, Ana Gonzalez-Alvarez, D. González-Chica, E. González-Gil, M. González-Gross, J. González-Rivas, Angel R. Gonzalez, Frédéric Gottrand, D. Grafnetter, A. Grajda, M. Grammatikopoulou, Tomasz Grodzicki, E. Grøholt, A. Grøntved, V. Guajardo, P. Guallar-Castillón, M. Guerchet, Ramiro Guerrero, A. Guimarães, U. Gujral, Martin C. Gulliford, M. Gunter, R. Gupta, O. Gureje, M. Gurinović, Beata Gurzkowska, Laura Gutiérrez, X. Gwee, R. Haghshenas, H. Hakimi, J. Halkjær, Ian R. Hambleton, B. Hamzeh, W. Hanekom, D. Hange, A. Hanif, S. Hantunen, J. Hao, Carla Menêses Hardman, Louise L. Hardy, R. H. Kumar, J. Harooni, S. M. Hashemi-Shahri, M. Hassapidou, Jun Hata, Teresa R. Haugsgjerd, M. Heinen, M. Hendriks, Rafael dos Santos Henrique, A. Henriques, L. H. Cadena, S. Herrala, M. Herrera-Cuenca, Victor M. Herrera, I. Herter-Aeberli, Karl-Heinz Herzig, R. Heshmat, Allan G. Hill, S. Ho, Michelle Holdsworth, R. Homayounfar, C. Homs, E. Hoogendijk, A. Horimoto, C. Hormiga, Bernardo L. Horta, L. Houti, C. Howitt, T. Htay, A. Htet, M. Htike, José María Huerta, I. Huhtaniemi, Laetitia Huiart, C. Petrescu, M. Huisman, Abdullatif S. Husseini, I. Huybrechts, N. Hwalla, L. Iacoviello, E. Iakupova, Anna G. Iannone, J. Igland, C. Ijoma, V. Iotova, V. Irazola, Takafumi Ishida, G. Isiguzo, Muhammad Islam, Sheikh Mohammed Shariful Islam, D. Islek, T. Ittermann, I. Ivanova-Pandourska, Masanori Iwasaki, T. Jääskeläinen, Rod Jackson, Hashem Y. Jaddou, M. Jadoul, T. Jafar, Nataša Jan, Edward Janus, J. Jarani, G. Jarnig, M. Jarvelin, G. Jasienska, A. Jelaković, B. Jelaković, A. Jha, Ramon O. Jimenez, K. Jöckel, Michel Joffres, J. Jokelainen, J. Jonas, P. Joshi, Rohina Joshi, J. Josipović, F. Joukar, J. Jozwiak, A. Juolevi, V. Jureša, V. Jureša, R. Kaaks, F. Kaducu, A. Kadvan, Anthony Kafatos, E. Kajantie · 发表于：The Lancet · 年份：2024 · DOI：10.1016/s0140-6736(24)01405-3 · 被引用次数：59 · 研究领域：Medicine

BACKGROUND Adiposity can be measured using BMI (which is based on weight and height) as well as indices of abdominal adiposity. We examined the association between BMI and waist-to-height ratio (WHtR) within and across populations of different world regions and quantified how well these two metrics discriminate between people with and without hypertension. METHODS We used data from studies carried out from 1990 to 2023 on BMI, WHtR and hypertension in people aged 20-64 years in representative samples of the general population in eight world regions. We graphically compared the regional distributions of BMI and WHtR, and calculated Pearson's correlation coefficients between BMI and WHtR within each region. We used mixed-effects linear regression to estimate the extent to which WHtR varies across regions at the same BMI. We graphically examined the prevalence of hypertension and the distribution of people who have hypertension both in relation to BMI and WHtR, and we assessed how closely BMI and WHtR discriminate between participants with and without hypertension using C-statistic and net reclassification improvement (NRI). FINDINGS The correlation between BMI and WHtR ranged from 0·76 to 0·89 within different regions. After adjusting for age and BMI, mean WHtR was highest in south Asia for both sexes, followed by Latin America and the Caribbean and the region of central Asia, Middle East and north Africa. Mean WHtR was lowest in central and eastern Europe for both sexes, i...