Adsorption of fluoroquinolones on hollow Co3S4 polyhedron sulfidated from ZIF-67 and its application of dispersed solid phase extraction prior to HPLC-UV.

作者：Youfang Qi, X. Dang, Huaixia Chen · 发表于：Analytica Chimica Acta · 年份：2025 · DOI：10.1016/j.aca.2025.344211 · 被引用次数：2 · 研究领域：Medicine

BACKGROUND Developing pretreatment technique with new adsorbent is essential to improve the detection sensitivity of trace fluoroquinolones (FQs) in complex sample. Zeolite imidazole skeleton-67 (ZIF-67) has adsorbability for FQs, but its structure of rhombohedral dodecahedra may reduce the efficiency of mass transfer, and its application is limited by the instability and poor recyclability. RESULTS A S-doped hollow Co3S4 polyhedron was prepared by sulfidation of ZIF-67 with thioacetamide and applied for disperse solid phase extraction (DSPE) of four FQs. SEM and TEM confirmed its hollow structure, the BET specific surface area was 40.17 m2/g and the adsorption capacity was up to 53.42 mg/g. The adsorption kinetics and isotherm of FQs on the Co3S4 polyhedron were investigated. The adsorption process was a chemisorption reaction, which depends on electrostatic interaction, surface complexation, π-π interaction and hydrogen bonding. A DSPE-HPLC-UV method based on the hollow Co3S4 polyhedron was developed to determine trace FQs. The method has broad linear range with LODs of 0.10-0.15 μg/kg and LOQs of 0.30-0.50 μg/kg. The intra-batch and inter-batch RSDs were less than 10 %. The recovery rate of FQs in honey samples was satisfactory. SIGNIFICANCE The hollow Co3S4 polyhedron has high extraction efficiency for FQs because of the large cavities. Its adsorption capacity was higher than some adsorbents and about 2-3 times than ZIF-67. It has better stability and repeatability. T...