Six-year follow-up of glycemic control and cardiovascular risk factors after a one-year intensive lifestyle intervention in type 2 diabetes: An extension of the randomized U-TURN trial

作者：Mette Y. Johansen, C. Durrer, N. S. Pilmark, Grit E. Legaard, K. Karstoft, K. B. Hansen, C. MacDonald, T. Almdal, J. Bjorner, N. W. Albrechtsen, A. Vaag, Robin Christensen, B. K. Pedersen, M. Ried-Larsen · 发表于：Journal of Sport and Health Science · 年份：2025 · DOI：10.1016/j.jshs.2025.101059 · 被引用次数：2 · 研究领域：Medicine

Highlights • Lifestyle interventions may decrease or even eliminate the short-term need for glucose-lowering medications in persons with short-standing type 2 diabetes.• What are the long-term effects of a 1-year lifestyle intervention aimed at reducing glucose-lowering medications on glycemic control and cardiometabolic risk factors in persons with a short duration (<10 years) of type 2 diabetes?• The benefits of a 1-year lifestyle intervention on HbA1c and cardiometabolic risk factors are not sustained 5 years after the 1-year intervention, and standard care is associated with more favorable diastolic BP control.• The management of non-glycemic risk factors should receive increased attention for persons living with type 2 diabetes who aim to achieve lifestyle-induced reductions in glucose-lowering medications.