Safety and Effectiveness of Blind Percutaneous Liver Biopsy: Analysis of 1412 Procedures

作者：A. Szymczak, K. Simon, M. Inglot, A. Gładysz · 发表于：Hepatitis Monthly · 年份：2012 · DOI：10.5812/kowsar.1735143x.4388 · 被引用次数：59 · 研究领域：Medicine

Background Percutaneous liver biopsy is one of the most important and widely used methods for diagnosing chronic liver diseases; however, controversies related to the potential risk of complications and patient discomfort still exist. Objectives The objective of this study was to evaluate the safety and success rate of blind percutaneous liver biopsy. Patients and Methods We conducted a retrospective analysis of 1412 blind percutaneous thick-needle liver biopsies performed during 1977-2000 at a single center on 1110 patients, using archived medical data of the center. Results The overall success rate of obtaining a liver sample with this method was 95.3%. Of all the samples assessed, 91.7% were determined to be fully representative for an evaluation by the pathologist. Complications occurred in 259 procedures (18.3%). While no fatalities associated with liver biopsy were noted, 9 serious complications (0.64%) directly related to biopsies were reported. Pain was the most common complication (15.3%). Significantly more complications (pain and vasovagal reactions) were reported in females (22.1%) than in males (16.1%) (P = 0.005). The rate of complications was significantly correlated with the stage of fibrosis (P = 0.027), i.e. the higher the fibrosis stage, the higher the complication rate. Previous surgical procedures involving the abdominal cavity or thorax influenced the effectiveness of liver biopsy (P = 0.017). Less operator experience was significantly associated with a ...