GINGIVAL FLUID AS A POTENTIAL OBJECT FOR DIAGNOSTICS PROCESS

作者：L. Ostrovskaya, Diana Beybulatova, N. Zakharova, L. Katkhanova, A. Lysov, A. Heigetyan, D. Domenyuk · 年份：2020 · DOI：10.35630/2199-885x/2020/10/2.27 · 被引用次数：4 · 研究领域：Medicine

occurs due to microbial penetration into the periodontal tissue. Gingival fluid can be employed as the fastest and most accurate reflection of pathological changes taking place in the cellular composition, the protein spectrum, and the pH status so this is of interest as a research object. The difference in the outcomes obtained through studying the cytokines level has been attributed to the use of different methods for sampling and storage of fluid samples. K E Y w O R D S — chronic generalized periodontitis, gingival fluid, cytokines. Larisa Ostrovskaya , Diana Beybulatova , Natalya Zakharova , Lilia Katkhanova , Alexander Lysov , Artur Heigetyan , Dmitry Domenyuk 1 Razumovsky Saratov State Medical University, Saratov; 2 Rostov State Medical University, Rostov; 3 Stavropol State Medical University, Stavropol, Russia ost-lar@mail.ru http://dx.doi.org/10.35630/2199-885X/2020/10/2.27 Received 30 March 2020; Received in revised form 5 May 2020; Accepted 21 May 2020 i n t r o d U C t i o n Periodontal diseases belong to multifactorial infections, resulting from disturbed interaction between various bacteria and the periodontal immune system cells. These processes lead to the release of an uncontrolled amount of pro-inflammatory cytokines and chemokines, which ultimately results in destroyed periodontal structures [1–7]. Gingival crevicular fluid (GCF) in persons with periodontal issues contains inflammatory cells, bacteria, tissue disintegration products, antibodies, the complem...