Expression of Concern

发表于：International Journal of Cancer · 年份：2021 · DOI：10.1002/ijc.33825 · 研究领域：Medicine

Iwase M, Watanabe H, Kondo G, Ohashi M, Nagumo M. Enhanced susceptibility of oral squamous cell carcinoma cell lines to FAS-mediated apoptosis by cisplatin and 5-fluorouracil. Int J Cancer. 2003 Sep 10;106(4):619-25. doi: 10.1002/ijc.11239. This Expression of Concern is for the above article, published online on May 30, 2003, in Wiley Online Library (wileyonlinelibrary.com), and has been published by agreement between the journal Editor-in-Chief, the first and corresponding author, Dr. Masayasu Iwase, and John Wiley & Sons, Ltd. The Expression of Concern has been agreed due to concerns regarding data presented in Figure 1, 5 and 6. In Figure 1B, in the right panel (HSC-4), bands #2-4 for FAS appear highly similar to bands #1-3 for GAPDH. In Figure 5A, bands for Procaspase-8 in “NA” appear similar to those for β-actin in “HSC-400. In Figure 5B, bands for c-FLIP in “NA” and for c-FLIP in “HSC-400 appear similar after brightness enhancement and vertical stretching. In Figure 6B, bands for β-actin in “NA” and” HSC-400 appear similar after vertical stretching. The authors have been unable to provide original data underlying these images due to the time that has elapsed. The corresponding author does not agree to the above-mentioned issues in Figure 5A + B, but states that the mistakes in Figure 1B and Figure 6B occurred accidentally. He provided alternative images for correction of the issues in Figure 1B and Figure 6B, but due to the lack of original raw data, the origin of these...