Alveolar soft part sarcoma of tongue in a 3-year-old Taiwanese

作者：Ching-Wei Hsu, C. Tseng, Wen-Chen Wang, Yuk-Kwan Chen · 发表于：Journal of Dental Sciences · 年份：2019 · DOI：10.1016/j.jds.2019.03.004 · 被引用次数：19 · 研究领域：Medicine

tps://doi.org/10.1016/j.jds.2019.03. 91-7902/a 2019Association for Denta e CC BY-NC-ND license (http://creati Alveolar soft-part sarcoma (ASPS), which was firstly described by Christopherson et al., in 1952, is a rare softtissue sarcoma accounting for approximately 0.5e1.0% of all soft tissue sarcomas and less than 0.1% of head and neck sarcomas. ASPS occurs predominantly in adolescents and young adult from the age of 15e35, and is very rare in age less than 5 years. Most ASPSs manifest as slow growing, painless intramuscular masses. Head and neck region is the most common affected site for cases of infants and children with 41% at the orbit and 25% in the oral cavity. We herein reported a case of ASPS in a 3-year-old boy who complained his tongue stabbed by a fishbone. His parents noted a swelling over his right posterior dorsal tongue for 3 months. Intraoral examination revealed a painless, pink-colored, round-shaped, smooth-surfaced submucosal rubbery swelling, measured about 1.2 0.8 cm in diameter, over the right posterior dorsal tongue (Fig. 1A). Neither tenderness nor cervical lymph node enlargement was noted. Tentative diagnosis was a foreign body granuloma. This lesion was subsequently excised under sedation (Fig. 1B, C). Histopathological examination showed sheets and lobules of tumor cells delineated by fibrous septa in the lamina propria of the mucosa (Fig. 1D). The tumor cells revealed eosinophilic, granular cytoplasm, and central or eccentric nuclei with prominen...