Probing N6-methyladenosine RNA modification status at single nucleotide resolution in mRNA and long noncoding RNA

作者：Nian Liu, M. Parisien, Qing Dai, G. Zheng, Chuan He, T. Pan · 发表于：RNA: A publication of the RNA Society · 年份：2013 · DOI：10.1261/rna.041178.113 · 被引用次数：474 · 研究领域：Biology、Medicine

It has long been a mystery as to the function(s) of N6-methyladenosine modifications in mRNAs. This paper describes a method to determine both the location and stoicheometry of such modified nucleotides in long RNAs. This method may provide clues regarding potential functions for m6A modifications.