Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015

作者：G. Roth, C. Johnson, A. Abajobir, F. Abd-Allah, S. Abera, G. Abyu, M. Ahmed, Baran Aksut, Tahiya Alam, K. Alam, F. Alla, N. Alvis-Guzmán, Stephen M. Amrock, H. Ansari, J. Ärnlöv, H. Asayesh, T. Atey, L. Ávila-Burgos, A. Awasthi, A. Banerjee, A. Barać, T. Bärnighausen, L. Barregard, Neeraj Bedi, Ezra Belay Ketema, D. Bennett, G. Berhe, Z. Bhutta, Shimelash Bitew, J. Carapetis, J. Carrero, D. Malta, C. Castañeda-Orjuela, Jacqueline Castillo-Rivas, F. Catalá-López, J. Choi, H. Christensen, M. Cirillo, Leslie T. Cooper, M. Criqui, D. Cundiff, A. Damasceno, L. Dandona, R. Dandona, K. Davletov, S. Dharmaratne, P. Dorairaj, M. Dubey, R. Ehrenkranz, M. El Sayed Zaki, E. J. Faraon, A. Esteghamati, T. Farid, M. Farvid, V. Feigin, Eric L. Ding, G. Fowkes, T. Gebrehiwot, R. Gillum, Audra Gold, P. Gona, R. Gupta, T. Habtewold, N. Hafezi-Nejad, T. Hailu, G. B. Hailu, G. Hankey, H. Hassen, K. H. Abate, Rasmus J. Havmoeller, Simon Iain Hay, M. Horino, P. Hotez, K. Jacobsen, S. James, Mehdi Javanbakht, P. Jeemon, D. John, J. Jonas, Yogeshwar V. Kalkonde, Chante Karimkhani, A. Kasaeian, Y. Khader, A. Khan, Y. Khang, Sahil Khera, A. Khoja, J. Khubchandani, Daniel H. Kim, D. Kolte, S. Kosen, Kristopher J. Krohn, G. Kumar, G. Kwan, D. Lal, A. Larsson, S. Linn, Alan D. Lopez, P. Lotufo, H. A. E. El Razek, R. Malekzadeh, M. Mazidi, T. Meier, K. G. Meles, G. Mensah, A. Meretoja, H. Mezgebe, T. Miller, E. Mirrakhimov, Shafiu Mohammed, Andrew E. Moran, K. Musa, J. Narula, B. Neal, F. Ngalesoni, Grant Nguyen, C. Obermeyer, M. Owolabi, G. Patton, J. Pedro, D. Qato, M. Qorbani, K. Rahimi, R. Rai, S. Rawaf, A. Ribeiro, S. Safiri, J. Salomon, I. Santos, Milena Šantrić Milićević, B. Sartorius, A. Schutte, S. Sepanlou, M. Shaikh, Min-Jeong Shin, M. Shishehbor, H. Shore, D. Silva, E. Sobngwi, S. Stranges, S. Swaminathan, R. Tabarés-Seisdedos, Niguse Tadele Atnafu, F. Tesfay, J. Thakur, A. Thrift, R. Topór-Mądry, T. Truelsen, S. Tyrovolas, K. Ukwaja, O. Uthman, T. Vasankari, V. Vlassov, S. Vollset, Tolassa Wakayo, D. Watkins, R. Weintraub, A. Werdecker, R. Westerman, C. Wiysonge, C. Wolfe, A. Workicho, Gelin Xu, Y. Yano, P. Yip, N. Yonemoto, M. Younis, Chuanhua Yu, T. Vos, M. Naghavi, C. Murray · 发表于：Journal of the American College of Cardiology · 年份：2017 · DOI：10.1016/j.jacc.2017.04.052 · 被引用次数：3327 · 研究领域：Medicine

Background The burden of cardiovascular diseases (CVDs) remains unclear in many regions of the world. Objectives The GBD (Global Burden of Disease) 2015 study integrated data on disease incidence, prevalence, and mortality to produce consistent, up-to-date estimates for cardiovascular burden. Methods CVD mortality was estimated from vital registration and verbal autopsy data. CVD prevalence was estimated using modeling software and data from health surveys, prospective cohorts, health system administrative data, and registries. Years lived with disability (YLD) were estimated by multiplying prevalence by disability weights. Years of life lost (YLL) were estimated by multiplying age-specific CVD deaths by a reference life expectancy. A sociodemographic index (SDI) was created for each location based on income per capita, educational attainment, and fertility. Results In 2015, there were an estimated 422.7 million cases of CVD (95% uncertainty interval: 415.53 to 427.87 million cases) and 17.92 million CVD deaths (95% uncertainty interval: 17.59 to 18.28 million CVD deaths). Declines in the age-standardized CVD death rate occurred between 1990 and 2015 in all high-income and some middle-income countries. Ischemic heart disease was the leading cause of CVD health lost globally, as well as in each world region, followed by stroke. As SDI increased beyond 0.25, the highest CVD mortality shifted from women to men. CVD mortality decreased sharply for both sexes in countries with an ...