Challenge and Chance of Single Atom Catalysis: The Development and Application of the Single Atom Site Catalysts Toolbox.

作者：Xiao Liang, Shuangchao Yao, Zhi Li, Yadong Li · 发表于：Accounts of Chemical Research · 年份：2025 · DOI：10.1021/acs.accounts.4c00857 · 被引用次数：83 · 研究领域：Medicine

ConspectusSingle atom catalysis has garnered widespread attention in the past decade. In general, single atom catalysis refers to a catalytic process involving the participation of single atom sites. A single atom site refers to an active site with only one metal atom playing the main role in the catalysis process. This metal atom is usually coordinated by other atoms in the active site and anchored on the support. Heterogeneous catalysts in which all active sites are single atom sites are referred to as single atom site catalysts (SASCs). Owing to their distinctive active site architecture, single atom catalysis has shown ultrahigh atomic utilization efficiency and unique catalytic activity and selectivity in many systems such as thermal catalysis, electrocatalysis, and environmental catalysis.However, the preparation of SASCs poses significant challenges as metal species tend to sinter and agglomerate during high-temperature treatment. In the past decade, we have challenged the controllable preparation of SASCs based on more than ten years of experience in nanomaterial synthesis. Several representative SASC preparation strategies have been proposed by our group, such as pyrolysis of MOFs with metal ions doped in the skeleton, M@ZIF-8 with a metal precursor fixed by the host-guest interaction, and M/N-rich support precursors. Additionally, "top-down" strategies starting from metal nanoparticles have been established. Based on these synthetic strategies, a systematic SASCs to...