Prime Editing: Precision Genome Editing by Reverse Transcription.

作者：Jun Yan, A. Cirincione, Britt Adamson · 发表于：Molecules and Cells · 年份：2020 · DOI：10.1016/j.molcel.2019.12.016 · 被引用次数：29 · 研究领域：Medicine、Biology

Genome editing is a method for making targeted sequence changes to the genomes of living cells. Prime editing, recently reported by Anzalone et al. (2019), is a new technology that uses reverse transcription to "write" programmed sequence changes into genomic DNA and thus promises significant technical advances.