Disrupted functional connectivity of the habenula links psychomotor retardation and deficit of verbal fluency and working memory in late‐life depression

作者：Ting Su, Ben Chen, Mingfeng Yang, Qiang Wang, Huarong Zhou, Min Zhang, Zhangying Wu, Gaohong Lin, Danpeng Wang, Yue-feng Li, Xiao-Mei Zhong, Yuping Ning · 发表于：CNS Neuroscience & Therapeutics · 年份：2023 · DOI：10.1111/cns.14490 · 被引用次数：6 · 研究领域：Medicine

Functional abnormalities of the habenula in patients with depression have been demonstrated in an increasing number of studies, and the habenula is involved in cognitive processing. However, whether patients with late‐life depression (LLD) exhibit disrupted habenular functional connectivity (FC) and whether habenular FC mediates the relationship between depressive symptoms and cognitive impairment remain unclear.