Outcomes of hemophagocytic lymphohistiocytosis in acute myeloid leukemia: the 3-site Mayo Clinic experience

作者：Jabra Zarka, Clifford M. Csizmar, Syeda Mina, Ashley Hickman, Erica L Andres, A. Matin, N. Gangat, T. Badar, A. Mangaonkar, Mirinal S Patnaik, M. Litzow, William J. Hogan, M. Torghabeh, James M. Foran, C. A. Yi, Mithun V. Shah, K. Begna, A. Al-Kali, H. Alkhateeb, Antoine N. Saliba · 发表于：Blood neoplasia · 年份：2026 · DOI：10.1016/j.bneo.2026.100223 · 被引用次数：1 · 研究领域：Medicine

Key Points • AML-associated HLH primarily affects older patients with genomically unstable AML and is independently associated with poor survival.• TP53 and DNA damage repair pathway mutations are associated with increased susceptibility to HLH in patients with AML.