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Atlas of lesion locations and postsurgical seizure freedom in focal cortical dysplasia: A MELD study

作者:K. Wagstyl, K. Whitaker, A. Raznahan, Jakob Seidlitz, P. Vértes, Stephen T. Foldes, Zachary Humphreys, Wen-Han Hu, Jiajie Mo, M. Likeman, Shirin Davies, M. Lenge, Nathan T. Cohen, Yingying Tang, Shan Wang, M. Ripart, A. Chari, M. Tisdall, N. Bargalló, E. Conde-Blanco, J. Pariente, Saül Pascual-Diaz, Ignacio Delgado-Martínez, C. Pérez-Enríquez, Ilaria Lagorio, E. Abela, N. Mullatti, J. O’Muircheartaigh, Katy Vecchiato, Yawu Liu, M. Caligiuri, B. Sinclair, L. Vivash, A. Willard, J. Kandasamy, A. McLellan, D. Sokol, M. Semmelroch, Ane G. Kloster, Giske Opheim, Clarissa Yasuda, Kai Zhang, K. Hamandi, C. Barba, R. Guerrini, W. Gaillard, X. You, I. Wang, S. González-Ortiz, M. Severino, P. Striano, D. Tortora, R. Kälviäinen, A. Gambardella, A. Labate, P. Desmond, Elaine H. Lui, T. O’Brien, J. Shetty, G. Jackson, J. Duncan, Gavin P. Winston, L. Pinborg, F. Cendes, J. H. Cross, T. Baldeweg, S. Adler · 发表于:Epilepsia · 年份:2021 · DOI:10.1111/epi.17130 · 被引用次数:103 · 研究领域:Medicine

Drug‐resistant focal epilepsy is often caused by focal cortical dysplasias (FCDs). The distribution of these lesions across the cerebral cortex and the impact of lesion location on clinical presentation and surgical outcome are largely unknown. We created a neuroimaging cohort of patients with individually mapped FCDs to determine factors associated with lesion location and predictors of postsurgical outcome.