Nuclear m(6)A Reader YTHDC1 Regulates mRNA Splicing.

作者：I. A. Roundtree, Chuan He · 发表于：Trends in Genetics · 年份：2016 · DOI：10.1016/j.tig.2016.03.006 · 被引用次数：1935 · 研究领域：Medicine、Biology

N(6)-Methyladenosine (m(6)A) is emerging as a chemical mark that broadly affects the flow of genetic information in various biological processes in eukaryotes. Recently, Xiao et al. reported that the nuclear m(6)A reader protein YTHDC1 impacts mRNA splicing, providing a transcriptome-wide glance of splicing changes affected by this mRNA methylation reader protein.