Targeted saliva metabolomics in Sjögren's syndrome

作者：Giovanna Piacenza Florezi, Felippe Pereira Barone, M. Izidoro, J. Soares-Jr, C. Coutinho-Camillo, S. V. Lourenço · 发表于：Clinics · 年份：2024 · DOI：10.1016/j.clinsp.2024.100459 · 研究领域：Medicine

Highlights • The role of metabolism in Sjögren's Syndrome (SS) is still under discussion.• Saliva can reflect the metabolic state of the microenvironments of salivary glands affected by SS.• An increase in metabolites associated with oxidative stress can be observed.• An increase in metabolites involved in the growth and proliferation of T-cells was also observed.