In-Hospital Rehabilitation for Frailty Management May Improve Quality of Life in Patients Receiving Maintenance Dialysis: A Retrospective Observational Study

作者：Yonemochi T, Ina K, Ina H, Morizane A, Kabeya M, Nagasaka M, Sakaguchi A, Taniguchi A, Nishiyama S, Ohta Y · 发表于：Cureus · 年份：2026 · DOI：10.7759/cureus.109144 · 被引用次数：23

Background Quality of life (QOL) is defined as an individual's perception of his or her position in life in the context of culture and value systems. Previous studies have shown that hemodialysis markedly affects patients' QOL, and health-related QOL has been increasingly recognized as an important medical outcome in patients undergoing maintenance hemodialysis (MHD). Methods A two-week hospitalization program for patients undergoing MHD was introduced in 2023 to evaluate frailty, along with comprehensive geriatric assessment (CGA) and evaluation of motor and oral cavity functions. During this program, QOL was assessed using the Kidney Disease Quality of Life-36 (KDQOL-36) questionnaire, and physical exercise was instructed according to the Japanese Renal Rehabilitation Guideline. After the incidence of each item was determined, the associations between these factors were retrospectively analyzed to identify the specific factors affecting QOL. Results QOL, as determined using the physical component summary (PCS) and mental component summary (MCS), decreased in more than 40% of the enrolled patients. Motor function was often impaired in patients undergoing MHD. In univariate analyses, the PCS score was strongly correlated with seven variables, including lower-limb strength/body weight (%), gait speed (5 m), the 6-minute walk test (6MWT), the Short Physical Performance Battery (SPPB), the Eating Assessment Tool-10 (EAT-10) score, the Tokyo Metropolitan Institute of Gerontology ...