Identification of vasculo-biliary anatomy using indocyanine green during laparoscopic cholecystectomy: A prospective observational study-the IVA green study

作者：Christopher A, Sharma SL, Gaikwad P, George AJ, Thomas CT, Lazarus E · 发表于：Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 年份：2026 · DOI：10.1007/s12664-025-01871-8 · 研究领域：Indocyanine Green、Cholecystectomy, Laparoscopic、Cystic Duct、Optical Imaging、Common Bile Duct、Arteries、Humans、Prospective Studies、Male、Female、Adult、Middle Aged

BACKGROUND AND OBJECTIVES: This study evaluated the feasibility and effectiveness of near-infrared fluorescence using indocyanine green (ICG) for intra-operative identification of cystic duct and artery anatomy, including aberrations, during laparoscopic cholecystectomy. METHODS: A prospective observational non-blinding study was conducted from November 2019 to February 2023, enrolling 67 adult patients scheduled for laparoscopic cholecystectomy. Indocyanine green (0.2 mg/kg) was administered six to 10 hours before surgery. Visualization of the cystic duct, common bile duct (CBD) and cystic artery was assessed using near-infrared fluorescence imaging. Univariate and multivariate analysis was done to identify the correlation between demographic and clinical factors with the identification of the cystic duct, CBD and cystic artery. Univariate and multivariate analysis was done to identify the correlation between gender and body mass index (BMI) with the identification of the cystic duct, CBD and cystic artery. RESULTS: The vasculo-biliary structures were visualized with ICG administration. The cystic duct was identified in 88%, the CBD in 92.6% and the cystic artery in 85% (Group-II variant was the commonest). Visualization of the cystic duct was significantly more difficult in male patients, while the visualization of the cystic artery was significantly reduced in patients with a > 25 kg/m2. CONCLUSIONS: Indocyanine green-based near-infrared fluorescence is a safe, feasible...