Cognitive Improvement in Children With Cerebral Palsy Following Combined Scalp Acupuncture and High-Frequency Repetitive Transcranial Magnetic Stimulation (rTMS): A Prospective Observational Study

作者：Shen XY, Zhao ZZ, Huang WY, Zhong JG · 发表于：Cureus · 年份：2025 · DOI：10.7759/cureus.87672 · 被引用次数：29 · 研究领域：cerebral palsy、cognitive improvement、high-frequency rtms、rehabilitation、scalp acupuncture

OBJECTIVE: To evaluate the clinical efficacy of combining scalp acupuncture and high-frequency repetitive transcranial magnetic stimulation (rTMS) for improving cognitive function in children with cerebral palsy (CP) and cognitive impairment.  Methods: In this prospective observational study, 60 children with CP and cognitive impairment were recruited from January 2023 to June 2024 at a tertiary rehabilitation center. Participants were divided into two groups (n=30 each): the observation group received scalp acupuncture plus high-frequency rTMS (3 sessions/week), while the control group received scalp acupuncture alone (same frequency). Both groups underwent concurrent routine rehabilitation (150 minutes/session, three sessions/week) for 24 weeks. Cognitive function was assessed using WISC-IV before and after intervention. Statistical analyses included t-tests, chi-square tests, and non-parametric tests. RESULTS: Baseline characteristics (age, gender, and disease duration) showed no differences between the two groups (p>0.05). Pre-intervention, compared with the control group, total WISC scores were higher (64.74±4.00 vs. 60.07±4.54, p＜0.001), and a greater proportion of children with mild cognitive impairment (25/30 vs. 14/30, p=0.037) were in the observation group. Post-intervention, compared with the control group, total WISC scores were higher (75.03±4.72 vs. 65.90±4.81, p＜0.001), 65.90±4.81，p＜0.001), mean change scores were increased (10.57±2.81 vs. 5.83±1.70, p＜0.001),...