Antigenotoxic Effect of Dominant Bacterial Isolates from Kimchi in vitro

作者：Junwon Choi, Jong‐Heum Park, Seung‐Taek Ji, Ok-Byung Choi, Heuyn‐Kil Shin · 发表于：Korean Journal of Food Science and Technology · 年份：1999 · 被引用次数：3 · 研究领域：Food Quality and Safety Studies、Nutrition, Health and Food Behavior、Agriculture, Soil, Plant Science

This study was carried out to isolate the colonies of dominant fermented bacteria from Kimchi (Korean native fermented foodstuffs) and investigate their inhibitory potentials on mutagenesis and carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) as direct carcinogen. For this purpose, single cell gel electrophoresis technique (SCGE assay, or comet assay) which is a sensitive and rapid technique for detecting the presence of DNA strand breaks in individual cells was used. DNA damages of Kimchi isolates were compared with that of the positive control, MNNG. Among 3 isolates from Tongbaechu Kimchi, two isolates B-1 and B-2 showed antigenotoxicities (p