Treatment of Cooley's anemia [see comments]

作者：Martin T. Fosburg, DG Nathan · 发表于：Blood · 年份：1990 · DOI：10.1182/blood.v76.3.435.435 · 被引用次数：127 · 研究领域：Streptococcal Infections and Treatments、Porphyrin Metabolism and Disorders、Heme Oxygenase-1 and Carbon Monoxide

The current approach to transfusion therapy of patients with Cooley's anemia was introduced by Wolman and subStantially modified in the mid 1970s.8-10The goals of transfusion therapy are twofold: to prevent anemia and to maintain a circulating hemoglobin (Hb) level sufficient to 021 15.The publication costs of this article were defrayed in part by page 'uppress endogenous erythropoiesis' The achievement Of erythroid marrow suppression is a major goal Of therapy charge payment, This article must therefore be hereby marked "advertisement" in accordance with 18 U.S.C. section 1734 solely to because ineffective erythropoiesis (due to unbalanced H b synthesis) leads to many of the disabling complications indicate this fact. 1990 by The American Society ofHematolo0.associated with thalassemia (Table 1).".12