Preoperative Factors Associated with Weight Loss and Recurrent Weight Gain after Bariatric Surgery: A Longitudinal Study in a UK Public Healthcare Setting

作者：Luqman Naim Bin Aizan, Akheel A. Syed, Bilal Alkhaffaf · 发表于：Obesity Surgery · 年份：2026 · DOI：10.1007/s11695-026-08900-1 · 研究领域：Bariatric Surgery and Outcomes、Cardiovascular Function and Risk Factors、Cardiovascular Disease and Adiposity

OBJECTIVE: Bariatric surgery is an effective treatment for obesity. This study aims to identify demographic factors of weight loss and recurrent weight gain over a 10-year follow-up period. METHODS: This retrospective observational study includes 2092 patients for overall trends, 1032 patients for predictors of weight loss, and 605 patients for predictors of recurrent weight gain. Percentage total weight loss (%TWL) trends were measured over 10 years. The rate of weight loss and recurrent weight gain was used as a response variable in multivariate analysis. RESULTS: After bariatric surgery, mean ± SD %TWL was greatest at 31.3 ± 10.7 % by 2 years, followed by gradual recurrent weight gain to a %TWL of 25.1 ± 12.6 % at 10 years. Up to 5 years, %TWL was greater with Roux-en-Y gastric bypass (n=1080; 27.9 ± 11.5 %) and one-anastomosis gastric bypass (n=217; 28.3 ± 10.1) had greater %TWL than sleeve gastrectomy (n=795; 22.8 ± 12.5 %) (ANOVA, p < 0.005). Age, sex, preoperative body mass index, diabetes, operation type, and smoking were statistically significant predictors of weight loss up to 2 years (p < 0.05). Age, hypertension, Index of Multiple Deprivation quintile, and early %TWL up to 2 years were statistically significant predictors of recurrent weight gain after 2 years (p < 0.05). CONCLUSIONS: Operation type, age, sex, preoperative body mass index, diabetes, operation type and smoking had significant associations with weight loss while age, hypertension, Index of Multiple ...