Unified definition of integrated diagnostics: a position statement of the EFLM

作者：Jochen K. Lennerz, Fabio Del Ben, Albrecht Stenzinger, Katrin Frauenknecht, Anna Carobene, Nino Berishvili, João Tiago Guimarães, L. Martí-Bonmatí, Reinhard Buettner, Verena Haselmann, Daniele Regge, Roberto Salgado, Mario Plebani, Pieter Vermeersch, Sergio Bernardini, Janne Cadamuro, Yale Tung-Chen, Norman Zerbe, Ian A. Cree, Michael Neumaier, Regina Beets-Tan, Pilar Fernandez Calle, Miriam A. Bredella, Tomris Özben · 发表于：Clinical Chemistry and Laboratory Medicine (CCLM) · 年份：2026 · DOI：10.1515/cclm-2026-0949 · 研究领域：Clinical Laboratory Practices and Quality Control、Clinical Reasoning and Diagnostic Skills、Healthcare cost, quality, practices

Abstract Integrated diagnostics is an emerging multidisciplinary model of care that integrates traditionally siloed domains, including pathology, radiology, genomics, and laboratory medicine, into a coordinated framework designed to improve diagnostic accuracy, treatment selection, and clinical outcomes. In this position statement, the EFLM Integrated Diagnostics Committee proposes a concise and operational definition of integrated diagnostics and outlines the relevance for healthcare systems. Integrated diagnostics has the potential to advance precision medicine through improved data integration, more coordinated interpretation, and enhanced clinical decision-making. Drawing on multidisciplinary expert consensus, we recommend adoption of a standardized conceptual framework to support research, clinical implementation, interoperability, and policy development across healthcare systems with implementation adapted to local needs, scale, and digital maturity.