Relationship among Sleep Disturbance, Stress, and Suicidal Ideation in Clinical High Risk for Psychosis

作者：Heather M. Wastler, Aubrey Moe, Alexandra M. Blouin, Melanie Bozzay, Melissa FV Kilicoglu, Celso Arango, Sylvain Bouix, Matthew R. Broome, Monica E. Calkins, Philippe Conus, Cheryl M. Corcoran, Courtney Crawford, Covadonga M. Díaz‐Caneja, Stefano Damiani, Paolo Fusar‐Poli, Matcheri S. Keshavan, Vijay A Mittal, Josh Nguyen, Jason Schiffman, Jai Shah, Walid Yassin, Alison R. Yung, Jean Addington, Luis Alameda, Kristin S Cadenhead, Ricardo E. Carrión, Rolando I Castillo-Passi, Eric Chen, Jimmy Choi, Barbara A Cornblatt, Lauren M. Ellman, Pablo A Gaspar, Carla Gerber, Louise Birkedal Glenthøj, Leslie E. Horton, Christy Lai Ming Hui, Joseph Kambeitz, Lana Kambeitz-Ilankovic, Minah Kim, Sung-Wan Kim, Nikolaos Koutsouleris, Jun Soo Kwon, Kerstin Langbein, Daniel Mamah, Daniel H. Mathalon, Merete Nordentoft, Godfrey D. Pearlson, Jesus Perez, Diana O. Perkins, Albert R. Powers, Jack Rogers, Fred W. Sabb, Steven M. Silverstein, Stefan Smesny, William S. Stone, Gregory P. Strauss, Judy L. Thompson, Rachel Upthegrove, Swapna Verma, Jijun Wang, Daniel H Wolf, Tianhong Zhang, Ofer Pasternak, Rene S Kahn, Martha E. Shenton, Patrick D. McGorry, Barnaby Nelson, John M. Kane, Carrie E Bearden, Scott W Woods, Lauren Addamo, Uzair Ahmed, Kelly Allott, Mario Álvarez‐Jiménez, G Paul Amminger, Rosie Arnold, Rebecca Beedham, Coco Beylot, Anusha Bharal, Sonia Birch, Kate Buccilli, Elle Butterworth, Eloise Cameron, John Chen, Ann Ee Ching, Beau-Luke Colton, Kate Conroy, Brittany Cook, Frederica Cooke, Simon D’Alfonso, Thomas Digby, Dominic Dwyer, Melanie Formica, Caroline Gao, Carmela Germano, Ruth Getachew, Larry Hendricks, Kevin Huynh, Sarah Joseph, Melissa Kerr, Hei Lam, Mahlee Langdon, Suzie Lavoie, Clarice Lee, Joshua Llerena, Brittany McQueen, Yohannes Mebrahtu, Inge van Meurs, Genevieve Middleton, Neal Morrell, Adibah Amani Nasarudin, Elle Nguyen, Sally O’Callaghan, Mariam Omar, Alice Partridge, Christina Phassouliotis, Matthew Phung, Andrea Polari, Marta Radosevic, Kate Reynolds, Keita Rudd, Shaheen Samnani, Isabelle Scott, Romy Schaumann, Angela Scheppokat, Raushaan Seychell, Amber Sherriff, Jashmina Shetty, Callum Snowball, Jessica Spark, Holly Still, Andrew Thompson, Michael Thwaites, Sophie Tod, Matilda Tonkovic, Cassandra MJ Wannan, Thomas J. Whitford, Sarah Whitson, Scott Williams, Stephen J. Wood, Rochelle Ruby Ye, Sarah Youn, Hok Pan Yuen, Alison R. Yung, Scott R. Clark, Marlene Früh, Igor Izyurov, Juliane Korittnik, Veronique Mann, Constantin Siegert, Frederick Tekook, Helle Gade Andersen, Anne Sofie Abildskov Dahl, Bjørn H. Ebdrup, Nikoline Rolver Elk, Anna Feveile, Kristina Ballestad Gundersen, Ulrich Lindberg, Anne Karen Nielse, Helle Schæbel, Mikkel Erlang Sørensen, Sofie Amalie Ege Sørensen, Daban KA Sulaiman, Chloe Clifford, Elizabeth Farrow, Paul Hicks, Dechante Johnson, Aanya Malaviya, Aissata Mavambu, Yasser Aleman, Livia Alerci, Marco Armando, Morgane Baumgartner, Martine Cleusix, Caroline Conchon, Kim Q, Khadimallah Ines, Raoul Jenni, Anastasie Jordan, Paul Klauser, Emylène Ostertag, T. Petrova, DaHye Jeon, Anna Jo, M. G. Lee, ChaeWon Park, JiMin Yoo, Mei San Ang, Yi Chian Chua, Darshan Dahjalarrajah, Hui En Lisa Koh, Jue Xin Janice Koi, Bing Cai Kok, Jia Ming Lau, Jimmy Lee, Voon Hao Lew, Yu Juan Lim, Siwei Cisy Liu, Wen Liang Loh, Amirah M Iskandar, Kwun Kei Eric Ng, Gurpreet Rekhi, Nathanael Tang, Yu Zheng Charmaine Tang, Yinghui Teng, Sin Yi Joice Tham, Pushpalata Tharumalingam, Swapna Verma, Jie Yin Yee, Hui Hui Michelle Yeo, Yichi Zhang, Juan Helen Zhou, Candice Yu Hay Chan, Lai Ming Christy Hui, Sonia Suet Ching Lo, Hui Lam Ng, Melody So, Yi Nam Suen, Ming Fung Tang, Tsz Lam Miriam Yeung, Öznur Baştürk, Annkathrin Böke, M Chakraborty, Sophie Fengler, Sophie Müller, Julian Wenzel, Tatiana Adasme, Alejandro Bruna, Pamela Contreras, Sebastián Corral, Pablo A Gaspar Ramos, Alejandro Maturana, Rocío Mayol-Troncoso, Pamela Paz, Manuel Reyes, Cesar Salinas, Gabriel Turra-Fariña, Daniela Valle, Francisco Zamorano, David Cotter, David Mongan, Jessica Hartmann, Naomi Wray, Hanneke Wigman, Laura L Adery, Monica Done, Gil D. Hoftman, Dylan Hughes, Kristen Laulette, Bernalyn Ruiz‐Yu, Jamie Zinberg, Rui Ma, Jennifer Betancourt, Vardui Grigoryan, Sparsh Moondhra, Vanessa Calderon, Simon Kapler, Katherine Karlsgodt, Andrea Vazquez Espinosa, Daisy Lopez, Oliver Flores, Misty C Richards, Debha Amatya, Danielle Denenny, Seohyun Joo, Sheena Salonga, Emily Martinez, Rachel McKinney, Jared Gilbert, Sergio Duron, Maria Golchin, Lorena Ruvalcaba, Grace Cai, Zachary Wong, Neda Awad, Tanya Diaz, Mary Rshtouni, Meghan Kussman, Monica Espana-Velasquez, Sullivan Salone, Wendy Zhang, Victoria Rosén, Lauren Trinidad, Alexis Worthley, Angela Jin, Remy Noveshen, Lisa Bartolomeo, Juliet Hagar, Haley Wang, Katherine Byrne, Rhideeta Jalal, Jee Won Kang, Masha Kotlyarevskiy, Dinisha Mingo, Arianna Mordy, Lingyan Yu, Brittney Sy, Petra Rupert, Melodie Yen, Brittany Wolff, Ella Bogomilsky, Carli Smythe, Nicole Swann, Meghan Davis-Reyes, Brett Barnes, Kelsey Schultz, Alexander Rockhill, Caghain McCoy, Daniel Brown, Jolinda Smith, Apoorva Karekal, Vince Quesada, Alex Holmes, Coleen Hudkins, Nicolas R. Bolo, Andrew Byun, Matcheri Keshavan, Erlend Lane, Jane Mikkelson, Carsten Langholm, Setari Parsa, Gennarina Santorelli, John Torous, Michelle Friedman-Yakoobian, Camille Evans, Walid Yassine, Highsmith Rich, Nikita Bansal, Margret Niznikiewicz, Lynda Tucker, Colette Potts, Danielle Larsen, Debra Tolstonog, Kalina Sabeva, Siyan He, Siyu Li, Olivia Aveson, Raquelle Mesholam-Gately, Amy Shalev, Araba Chintoh, BG Goodyear, Cari Jahraus, Emma Truscott, Erin Jones, Lu Liu, Karl Jungert, Monica Chu, Paul Romo, Amanda Chao, Dominique Bonneville, Jacqueline Stowkowy, Kali Brummitt, Kristin Minara, Ruth Olsen, Timothy Michaels, Xiang He, Michael Birnbaum, Mitchell Arnovitz, Andrea Auther, Ricardo E. Carrión, Patricia Marcy, Priya Matneja, Danielle McLaughlin, Susan Ray, Lauren Serrano, Nilda Rivera-Reyes, Rachel F Bleggi, Clark D Jeffries, Jenna Barbee, Sree Gogineni, Abigail Shuman, Amanda Neal, Cecilia Pearson Sousa, Daphney Bryan, Earl McBride, Elena Pokowitz, Rohan Kumar, Amber Leinward, Ayşenil Belger, Brittany Weir, Calli Holshouser, Camila Vallebona, Christian Santos, Daniel Kutuzov, Emily Hammer, Idil Baran, Jennifer Nieri, Karen Ecsedy, Nicholas Sheppard, Rachel F Bleggi, Shreeya Yarlagadda, Soliha Norbekova, Victor Pincay, Erica Oake, Averi Goldman, Emilie Powell, Marissa Mulea, Asher Alexander, Ewa Zapala, Jasper Mark, Sevde Aksoy, Erika Allison, Claire Deen, Anjali Chandrasekhar, Aidan Blumsack, Eliza List, Catherine Spencer, Danielle Pratt, Franchesca Kuhney, Gabrielle Olson, Isabelle Frosch, Ivanka Ristanovic, Jessica Fattal, Joanna Hernandez, Julie Kwon, Katherine Damme, Luz Maria Alliende Serra, Madison Stevens, Sophia Parmacek, Stew Shankman, Trevor Williams, Vanessa Zarubin, Vijay Mittal, Cameron Martinez, Chloe Krugel, Erica Karp, Gillian Ho, Jadyn Park, Juston Osborne, Kathy Moran, Kelly Bates, Maksim Giljen, Zachary Anderson, Jiayi Lin, Vereena Metry, Leda Kennedy, Heline Mirzakhanian, Chérine Akkari, Tyrone D. Cannon, Youngsun Cho, Nicole Santamauro, Kangjoo Lee, Masih Rahmati, Jie Lisa Ji, Catalina V Mourgues, Ángela Núñez, Munaza Ali, Alan Anticevic, Clara Fonteneau, Karlos J Mate Piovanetti, Holly Enden, JENNA GANNON, Brandon Asika Etuka, Albert RIII Powers, Vinod H. Srihari, Zailyn Tamayo, Emily Farina, Mara Heneks, Samuel Brege, Barbara C. Walsh, Alvaro Granados, Seyenah Lopez, Terry Camarro, John Cahill, Holly Hamilton, Spero C Nicholas, Lenie Torregrossa, Renée Dembo · 发表于：Deakin Research Online (Deakin University) · 年份：2026 · DOI：10.26187/deakin.33117518 · 研究领域：Sleep and related disorders、Suicide and Self-Harm Studies、Sleep and Wakefulness Research

Background and Hypothesis: Sleep disturbance is a well-established risk factor for suicide, though few studies to date have examined whether sleep disturbance contributes to suicide risk among individuals at clinical high risk for psychosis (CHR). The current study addressed this gap in the literature. We hypothesized that sleep disturbance would have a unique relationship with suicidal ideation/attempts when accounting for other variables in the model. We also hypothesized that the interaction between sleep disturbance/attenuated positive symptoms and sleep disturbance/stress would be related to suicidal ideation/attempts in CHR. Study Design: The current study used data generated by the Accelerating Medicines Partnership® Schizophrenia Observational Study. The total sample included 1,048 participants (827 CHR and 221 community controls). Participants completed measures of suicidal ideation/attempts, attenuated positive symptoms, depressive symptoms, perceived stress, and sleep disturbance. Study Results: Results supported a relationship between sleep disturbance and suicidal ideation/attempts in CHR, with participants who had lifetime ideation and attempts experiencing more sleep disturbance than those with no ideation or attempts. We also found small, but significant positive correlations between sleep disturbance and suicide risk in CHR. When accounting for other variables in the model, the effect of sleep disturbance remained significant for past month ideation, but not ...