Xenium in situ spatial transcriptomics of the amygdala and striatum in an α-synuclein preformed-fibril mouse model of Parkinson's disease

作者：Tingyang Yu, Chanakya Ekbote, N. V. Morozov, Antonio Herrera, Jiashuo Fan, Albert Dominguez Mantes, Salvatore Novello, Hilal A. Lashuel, Pascal Frossard, Stéphane d'Ascoli, Gioele La Manno, Maria Brbić · 发表于：Figshare · 年份：2026 · DOI：10.6084/m9.figshare.33017210.v1 · 研究领域：Neuroscience、Biology、Cell biology、Chemistry

Xenium In Situ spatial transcriptomics data from mouse brain sections in an α-synuclein preformed-fibril (PFF) model of Parkinson's disease, generated to support the study "Tissue Reconstruction with Generative AI" (Yu et al.).Control sections and harvested 3 months post-injection (3MPI) sections cover the amygdala and striatum of the whole sphere of brain. The predesigned 248-gene Xenium Mouse Brain Gene Expression panel was profiled across all sections on the Xenium in situ platform (10x Genomics).