Supplementary Figure S4 from Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy from a First-in-Human Study of Volrustomig, a Novel PD-1/CTLA-4 Bispecific Antibody

作者：Ben Tran, Mark Voskoboynik, Sang‐We Kim, Charlotte Lemech, Enric Carcereny, Sun Young Rha, Myung‐Ju Ahn, Enriqueta Felip, Ki Hyeong Lee, Eduardo Castañón Álvarez, James Chih‐Hsin Yang, Paolo A. Ascierto, Mariano Provencio, Shunsuke Kondo, Yasutoshi Kuboki, Daniel Freeman, Xuyang Song, Jorge Blando, Steven Eck, Florian Song, Zoey Tang, Michael Kuziora, Shelby D. Gainer, Patrick Mitchell, Julie M. Asare, Amal Ayyoub, Ikbel Achour, Deepa S. Subramaniam, Seock‐Ah Im · 年份：2026 · DOI：10.1158/1078-0432.33014550 · 研究领域：Medicine、Cancer research、Immunology、Internal medicine、Oncology

<p>Supplementary Figure S4. Molecular response dynamics (ctDNA) across all dose levels (225–2500 mg). Percent change from baseline in mVAF up to week 6.</p>