Ultrasound-mediated piezoelectricity enhancement in bioresorbable polymers

作者：Xinchang Kang, Y Li, Ruiyue Zhao, Y Yuan, Qi Chen, Pengyu Li, Zhengbao Yang, Jianglin Wang · 发表于：Bioactive Materials · 年份：2026 · DOI：10.1016/j.bioactmat.2026.06.039 · 研究领域：Advanced Sensor and Energy Harvesting Materials、Ultrasound Imaging and Elastography、Dielectric materials and actuators

Piezoelectric materials can power self-sustained medical devices, but biodegradable systems with high performance remain elusive. We introduce a high-frequency ultrasound treatment strategy that enhances the piezoelectricity of poly-L-lactide (PLLA) via standing-wave-induced crystallization and ferroelectric electret formation. Ultrasound at 1.2 MHz promotes β-form crystal alignment, increasing the piezoelectric coefficient ( d 33 ) to 10.8 pC/N, approaching that of non-degradable PVDF. The ultrasound-treated PLLA (US-PLLA) retains full biodegradability and biocompatibility, safely degrading in vivo without organ toxicity. Functionally, US-PLLA enables real-time biosignal monitoring and promotes cardiac recovery after myocardial infarction in rats. This work establishes ultrasound-mediated crystallization as a general route to high-performance biodegradable piezoelectric polymers for transient biomedical systems.