Dietary folic acid coordinates growth and lipid metabolism through gut microbial and one-carbon networks in juvenile mud crab (Scylla paramamosain).

作者：Zheng Tang, Yao Deng, Shichao Xie, Wenhao Zhan, Hongyu Peng, Yinqiu Tian, Min Jin, Tiantian Xu, Xishuai Cui, Xiaoyue Li, Peng Sun, Qicun Zhou · 发表于：PubMed · 年份：2026 · DOI：10.1016/j.aninu.2026.01.019 · 研究领域：Biological Research and Disease Studies、Aquaculture Nutrition and Growth、Invertebrate Immune Response Mechanisms

< 0.05), while reducing oxidative stress-tolerant, anaerobic, and potentially pathogenic bacteria in the intestine. These findings indicate that juvenile mud crab have a limited capacity for FA synthesis and require dietary supplementation. A dietary FA level of 4.26 mg/kg supported optimal growth and physiological functions, while two-slope broken-line regression of PWG against dietary FA levels estimated an optimal dietary requirement of 3.86 mg/kg for juvenile mud crab.