Breast Cancer Survival in Asian American Patients

作者：Scarlett Lin Gomez, Julie Von Behren, Valerie McGuire, Mi-Ok Kim, Luna Gao, Salma Shariff‐Marco, Katherine Lin, Iona C. Cheng, Marilyn L. Kwan, Anna H. Wu, Esther M. John, Lenora Loo, Allison W. Kurian, Jocelyn Koo, Lia D’Addario, Janise M. Roh, Isaac Joshua Ergas, Esperanza Castillo, Christine B. Ambrosone, Brittany N. Morey, Lawrence H. Kushi, Song Yao · 发表于：JAMA Network Open · 年份：2026 · DOI：10.1001/jamanetworkopen.2026.21041 · 被引用次数：1 · 研究领域：Global Cancer Incidence and Screening、Cancer Risks and Factors、Breast Cancer Treatment Studies

Importance: In the US, breast cancer mortality is lower among Asian American females diagnosed with breast cancer compared with other racial and ethnic groups, although reasons for this difference are not well understood. Objective: To examine contributions of clinical, lifestyle, and sociodemographic factors to mortality differences among females identifying as Asian races and ethnicities compared with non-Latina White females and whether associations vary by nativity. Design, Setting, and Participants: This cohort study analyzed time-to-event survival data from Asian and White females with breast cancer from 4 epidemiologic studies. Cohorts were recruited from California and Hawaii, with information from questionnaires and cancer registries. Participants were females with first primary invasive breast cancer diagnosed from 1992 to 2019 who self-identified as Asian and females who self-identified as White as a comparison group. Analyses were conducted from February 2024 to February 2026. Exposures: Self-reported race and ethnicity, nativity, clinical factors (eg, stage and tumor grade), marital status, educational level, reproductive factors, insurance status, lifestyle factors (eg, smoking and alcohol use), diabetes, and neighborhood socioeconomic indicators. Main Outcomes and Measures: The outcomes of interest were all-cause and breast cancer-specific mortality. Cox proportional hazards models were used to estimate hazard ratios (HRs) comparing each Asian group with White ...