Supplemental Figure 2 from Increased Glucose Availability Sensitizes Pancreatic Cancer to Macrophage-Targeting Immunotherapies
作者:Jonathan J. Hue, Mehrdad Zarei, Priyashree Sunita, Sami O. Abul-Khoudoud, Goutam Dey, Hallie J. Graor, Katie E. Blise, Dove Keith, Shamilene Sivagnanam, Shakti Prasad Pattanayak, Erryk Katayama, Omid Hajihassani, Charles D. Lopez, Rosalie C. Sears, Robert Eil, Lisa M. Coussens, Jonathan R. Brody, Ali Vaziri‐Gohar, Jordan M. Winter · 年份:2026 · DOI:10.1158/2767-9764.32769820 · 研究领域:Immune cells in cancer、Phagocytosis and Immune Regulation、Cancer Cells and Metastasis
<p>Supplemental Figure 2 - Macrophages differentially affect KPC cell growth based on polarization. Co-culture clonogenic assay of KPC cells with M1- or M2-like bone marrow-derived macrophages. Macrophages without KPC cells are depicted for reference. Relative KPC survival was assessed by quantification of luminescence of luciferase-expressing KPC cells after luciferin supplementation. Background luminescence of macrophages was subtracted. *** indicates p<0.001.</p>