Figure S1 from ETC-501 Is a Brain-Penetrant MNK Inhibitor That Potentiates TMZ-Induced Senescence and Sensitizes Glioblastoma Cells to Senolytic Therapy

作者：Giselle Sek Suan Nah, Yuk Kien Chong, Fatin Nasha Sulaimi, Kian Leong Lee, See Wee Lim, Qing You Pang, Mengge Yu, Zhen Wei Neo, Jabed Iqbal, Kassoum Nacro, Jeffrey Hill, Alex Matter, Henry Yang, Beng Ti Ang, Carol Tang, S. Tiong Ong · 年份：2026 · DOI：10.1158/0008-5472.32714901 · 研究领域：Melanoma and MAPK Pathways、Glioma Diagnosis and Treatment、Genetics and Neurodevelopmental Disorders

<p>High MNK1 expression is associated with enrichment of aggressive molecular features in therapy-treated GBM patients</p>