Figure S6 from DROSHA Regulates Mesenchymal Gene Expression in Wilms Tumor

作者：Patricia D.B. Tiburcio, Kavita Desai, Jiwoong Kim, Qinbo Zhou, Lei Guo, Xue Xiao, Li Zhou, Aysen Yuksel, Daniel Catchpoole, James F. Amatruda, Lin Xu, Kenneth Chen · 年份：2026 · DOI：10.1158/1541-7786.32714559 · 研究领域：Renal and related cancers、MicroRNA in disease regulation、Genomics, phytochemicals, and oxidative stress

<p>Supplementary Figure S6. Metabolomics of Wilms tumors were used to determine differential abundance of metabolites, expressed as log2-fold-change in tumors with microRNA processing mutations versus without such mutations, demonstrating that the antioxidant BH<sub>4</sub> is depleted in tumors with microRNA processing mutations.</p>