Table S2 from Paradoxical Activation of Oncogenic Signaling as a Cancer Treatment Strategy

作者：Matheus Henrique Dias, Anoek Friskes, Siying Wang, João M. Fernandes Neto, Frank van Gemert, Soufiane Mourragui, Chrysa Papagianni, Hendrik J. Kuiken, Sara Mainardi, Daniel Álvarez‐Villanueva, Cor Lieftink, Ben Morris, Anna Dekker, Emma van Dijk, Lieke H.S. Wilms, Marcelo S. da Silva, Robin A. Jansen, Antonio Mulero‐Sánchez, Elke Malzer, August Vidal, Cristina Santos, Ramón Salazar, Rosangela A.M. Wailemann, Thompson E.P. Torres, Giulia De Conti, Jonne A. Raaijmakers, Pétur Snæbjörnsson, Shengxian Yuan, Wenxin Qin, John S. Kovach, Hugo A. Armelin, Hein te Riele, Alexander van Oudenaarden, Haojie Jin, Roderick L. Beijersbergen, Alberto Villanueva, René H. Medema, René Bernards · 年份：2026 · DOI：10.1158/2159-8290.32697711 · 研究领域：Virus-based gene therapy research、Cytokine Signaling Pathways and Interactions、CRISPR and Genetic Engineering

<p>Supplementary table 2: Full list of genes whose overexpression was selectively toxic in the presence of LB-100 in HT-29 cells in the CRISPRa screen FDR smaller or equal to 0.25 and log2 fold change smaller or equal to -1 in treated/untreated comparison were criteria for hit selection.</p>