Supplementary Figure 1 from <i>KRAS</i> Loss of Heterozygosity Promotes MAPK-Dependent Pancreatic Ductal Adenocarcinoma Initiation and Induces Therapeutic Sensitivity to MEK Inhibition

作者：Sigrid K. Fey, Arafath K. Najumudeen, Dale M. Watt, Laura M. Millett, Catriona A. Ford, Kathryn Gilroy, Robert U. Simpson, Kathy McLay, Rosanna Upstill‐Goddard, David K. Chang, William Clark, Colin Nixon, Joanna L. Birch, Simon T. Barry, Jennifer P. Morton, Andrew D. Campbell, Owen J. Sansom · 年份：2026 · DOI：10.1158/0008-5472.32696882 · 研究领域：Melanoma and MAPK Pathways、NF-κB Signaling Pathways、Protein Tyrosine Phosphatases

<p>Increased fibrosis in wild-type Kras deficient PanINs.</p>