Supplementary Figure 7 from Lactate-Driven IL8<sup>+</sup> Tumor-Associated Macrophages Mediate Immunosuppression and Resistance to Immunotherapy in Clear-Cell Renal Cell Carcinoma

作者：Yu Dong, Wenbin Jiang, Youqi Qiu, Ziyang Xu, Jiangting Cheng, Peiqing Ke, Siyuan Dai, Yang Qu, Yu Xia, Jianming Guo, Li Liu, Jiejie Xu · 年份：2026 · DOI：10.1158/1078-0432.32709230 · 研究领域：Immune cells in cancer、Cancer, Hypoxia, and Metabolism、Ferroptosis and cancer prognosis

<p>Lactate-induced IL8 expression in macrophages is dependent on MCT-1-mediated lactate transport.</p>