Figure S16 from VGF-Mediated Mitochondrial Remodeling Fuels Lung Adenocarcinoma Brain Metastasis

作者：Yibei Wang, Xinyue Sheng, Yi Yang, Chen Liu, Shubao Wang, Ruixi Guo, Yue Gu, Ming Chen, Hongyan Zhang, Jingjing Du, Xiaoxue Qin, Ziwei Miao, Pengfei Wu, Xiujuan Qu, Bo Li · 年份：2026 · DOI：10.1158/0008-5472.32713302 · 研究领域：Mitochondrial Function and Pathology、Cell death mechanisms and regulation、Cancer, Hypoxia, and Metabolism

<p>Fig S16. Viability alterations in VGF-overexpressing cells following ABHD12B knockdown mediated by RNA interference. A, Q-PCR to measure the expression level of ABHD12B in VGF OE LUAD cells treated with si-ABHD12B. (mean±SD, n=3 per group) B, Cell viability of in VGF OE LUAD cells treated with si-ABHD12B. (mean±SD, n=3 per group) C, Scatter plots of flow cytometry analysis for cell death in VGF OE LUAD cells treated with si-ABHD12B by Annexin V/PI staining. D and E, Quantification of apoptotic cells by Annexin V/PI staining in VGF OE A549 (D) and H1299 (E) cells treated with si-ABHD12B. (mean±SD, n=3 per group) *, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, P < 0.0001; ns, not significant.</p>