Figure S14 from SOS1 Inhibition Enhances the Efficacy of KRAS<sup>G12C</sup> Inhibitors and Delays Resistance in Lung Adenocarcinoma

作者：Brianna R. Daley, Nancy E. Sealover, Bridget A. Finniff, Jacob M. Hughes, Erin Sheffels, Daniel Gerlach, Marco H. Hofmann, Kaja Kostyrko, Joseph P. LaMorte, Amanda J. Linke, Zaria Beckley, Andrew M. Frank, Robert E. Lewis, Matthew D. Wilkerson, Clifton L. Dalgard, Robert L. Kortum · 年份：2026 · DOI：10.1158/0008-5472.32697361 · 研究领域：Sphingolipid Metabolism and Signaling、PI3K/AKT/mTOR signaling in cancer、Protein Kinase Regulation and GTPase Signaling

<p>SOS1 and SOS2 protein abundance is stable in G12Ci DTPs.</p>