Figure S12 from SOS1 Inhibition Enhances the Efficacy of KRAS<sup>G12C</sup> Inhibitors and Delays Resistance in Lung Adenocarcinoma

作者：Brianna R. Daley, Nancy E. Sealover, Bridget A. Finniff, Jacob M. Hughes, Erin Sheffels, Daniel Gerlach, Marco H. Hofmann, Kaja Kostyrko, Joseph P. LaMorte, Amanda J. Linke, Zaria Beckley, Andrew M. Frank, Robert E. Lewis, Matthew D. Wilkerson, Clifton L. Dalgard, Robert L. Kortum · 年份：2026 · DOI：10.1158/0008-5472.32697367 · 研究领域：Protein Kinase Regulation and GTPase Signaling、Sphingolipid Metabolism and Signaling、Tuberous Sclerosis Complex Research

<p>G12Ci DTPs show reduced G12Ci engagement after washout.</p>