Figure S5 from ETC-501 Is a Brain-Penetrant MNK Inhibitor That Potentiates TMZ-Induced Senescence and Sensitizes Glioblastoma Cells to Senolytic Therapy
作者:Giselle Sek Suan Nah, Yuk Kien Chong, Fatin Nasha Sulaimi, Kian Leong Lee, See Wee Lim, Qing You Pang, Mengge Yu, Zhen Wei Neo, Jabed Iqbal, Kassoum Nacro, Jeffrey Hill, Alex Matter, Henry Yang, Beng Ti Ang, Carol Tang, S. Tiong Ong · 年份:2026 · DOI:10.1158/0008-5472.32714886 · 研究领域:Telomeres, Telomerase, and Senescence、Melanoma and MAPK Pathways、Glioma Diagnosis and Treatment
<p>ETC-501 enhances TMZ-induced senescence while attenuating SASP in GBM cell lines</p>