Supplementary Figure S14 from Mechanisms of Response and Tolerance to Active RAS Inhibition in KRAS-Mutant Non–Small Cell Lung Cancer
作者:Haniel A. Araújo, Ximo Pechuan-Jorge, Teng Zhou, Minh Truong, Xin Hu, Frank Rojas, Maria E. Salvatierra, Heladio P. Ibarguen, Richard Lee, Rashi Raghulan, Harshit Shah, Mariela A. Moreno Ayala, Kevin Chen, Nataliya Tovbis Shifrin, Shuhong Wu, Luisa M. Solis Soto, Marcelo V. Negrão, Don L. Gibbons, David S. Hong, Jack A. Roth, John V. Heymach, Jianjun Zhang, Jingjing Jiang, Mallika Singh, Jacqueline A.M. Smith, Elsa Quintana, Ferdinandos Skoulidis · 年份:2026 · DOI:10.1158/2159-8290.32699980 · 研究领域:Melanoma and MAPK Pathways、Protein Kinase Regulation and GTPase Signaling、Lung Cancer Treatments and Mutations
<p>Supplementary Figure S14. Mucinous tumor cells exhibit higher baseline expression of phospho-ERK1/2 and relative refractoriness to MAPK suppression following treatment with RMC-7977.</p>