Figure S8 from SOS1 Inhibition Enhances the Efficacy of KRAS<sup>G12C</sup> Inhibitors and Delays Resistance in Lung Adenocarcinoma

作者：Brianna R. Daley, Nancy E. Sealover, Bridget A. Finniff, Jacob M. Hughes, Erin Sheffels, Daniel Gerlach, Marco H. Hofmann, Kaja Kostyrko, Joseph P. LaMorte, Amanda J. Linke, Zaria Beckley, Andrew M. Frank, Robert E. Lewis, Matthew D. Wilkerson, Clifton L. Dalgard, Robert L. Kortum · 年份：2026 · DOI：10.1158/0008-5472.32697319 · 研究领域：Protein Kinase Regulation and GTPase Signaling、PI3K/AKT/mTOR signaling in cancer、Tuberous Sclerosis Complex Research

<p>SOS2 expression determines the extent of G12Ci:SOS1i synergy.</p>