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Figure S18 from VGF-Mediated Mitochondrial Remodeling Fuels Lung Adenocarcinoma Brain Metastasis

作者:Yibei Wang, Xinyue Sheng, Yi Yang, Chen Liu, Shubao Wang, Ruixi Guo, Yue Gu, Ming Chen, Hongyan Zhang, Jingjing Du, Xiaoxue Qin, Ziwei Miao, Pengfei Wu, Xiujuan Qu, Bo Li · 年份:2026 · DOI:10.1158/0008-5472.32713296 · 研究领域:S100 Proteins and Annexins、Cancer, Hypoxia, and Metabolism、Mitochondrial Function and Pathology

<p>Fig S18. VGF binding to ABHD12B affects lung adenocarcinoma cell viability. A and B, Viability curves of A549 (A) and H1299 (B) cells transfected with each fragment of VGF and ABHD12B. (mean±SD, n=3 per group) C and D, Cell viability of A549 (C) and H1299 (D) cells transfected with each fragment of VGF and ABHD12B at the 96-hour time point. (mean±SD, n=3 per group) E, Colony formation assay of LUAD cells transfected with each fragment of VGF and ABHD12B. F and G, Statistical results of the colony formation assay of A549 (F) and H1299 (G) cells transfected with each fragment of VGF and ABHD12B. (mean±SD, n=3 per group) *, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, P < 0.0001; ns, not significant.</p>