Supplementary Figure 2 from <i>KRAS</i> Loss of Heterozygosity Promotes MAPK-Dependent Pancreatic Ductal Adenocarcinoma Initiation and Induces Therapeutic Sensitivity to MEK Inhibition

作者：Sigrid K. Fey, Arafath K. Najumudeen, Dale M. Watt, Laura M. Millett, Catriona A. Ford, Kathryn Gilroy, Robert U. Simpson, Kathy McLay, Rosanna Upstill‐Goddard, David K. Chang, William Clark, Colin Nixon, Joanna L. Birch, Simon T. Barry, Jennifer P. Morton, Andrew D. Campbell, Owen J. Sansom · 年份：2026 · DOI：10.1158/0008-5472.32696876 · 研究领域：NF-κB Signaling Pathways、Pancreatic and Hepatic Oncology Research、Melanoma and MAPK Pathways

<p>Release from AZD6244 treatment results in rapid acinar to ductal metaplasia in KC KrasG12D/fl.</p>