Using a multistate model (N = 12,674), we examined the associations between reproductive endocrine hormones and transitions among three states in infertile patients.

作者：Yajun Dong (14666387), Zhonghua Ai (22758795), Shuhong Luo (387711), Yue Yang (52715), Yan Huang (46805), Dan Zhang (51283), Yan Jia (198590), Hongxia Ye (14666384) · 发表于：Figshare · 年份：2026 · DOI：10.1371/journal.pone.0349394.g003 · 研究领域：Medicine、Physiology、Endocrinology、Biology、Gynecology、Obstetrics、Internal medicine、Andrology

Hazard ratios are represented by bold lines, with 95% confidence intervals indicated by shaded areas. In the eight figures depicting the relationships of AMH and LH with the three state transitions (from infertility to biochemical pregnancy, biochemical pregnancy to clinical pregnancy, and clinical pregnancy to live birth) and AFC with the transitions from infertility to biochemical pregnancy and from biochemical pregnancy to clinical pregnancy, the P-values for non-linearity tests were all less than 0.05. Additionally, the P-values for non-linearity tests in the remaining figures were all greater than 0.05. Note: AMH, Anti-mullerian hormone; AFC, Antral Follicle Count; FSH, Follicle Stimulating Hormone; LH, Luteinizing Hormone; E2, Estradiol; P, Progesterone; TSH, Thyroid-Stimulating Hormone.