Patient-reported outcome measures used in studies of palliative surgery in cancer care: a scoping review

作者：Bonnie O. Wong, Sophie Nader, Jolene Si Min Wong, Xinyi Casuarine Low, Orly N. Farber, Jason B. Liu, Elizabeth J. Lilley · 发表于：Annals of Palliative Medicine · 年份：2026 · DOI：10.21037/apm-2025-1-147 · 研究领域：Palliative Care and End-of-Life Issues、Management of metastatic bone disease、Cancer survivorship and care

BACKGROUND: Palliative surgery aims to alleviate symptoms and enhance health-related quality of life (HRQL) for patients with incurable cancer. Standardized patient-reported outcome measures (PROMs) are needed to assess effects of interventions, including HRQL from patient perspectives. A previously published systematic review (Wong et al., 2025) identified studies of palliative cancer surgery; the present study is a secondary scoping review to identify and characterize patient-reported measures of HRQL in these studies. METHODS: We searched PubMed, EMBASE, and CINAHL databases to identify English-language publications (August 1, 2005-December 31, 2023) reporting palliative thoraco-abdominal procedures for cancer patients. Of these, studies reporting patient-reported HRQL outcomes were secondarily analyzed using descriptive and thematic analysis. RESULTS: Screening of 1,915 unique studies yielded 92 studies of which 16 (17.4%) included a patient-reported HRQL outcome, 11 of which used a total of 13 unique validated PROMs. Five studies which used investigator-developed (non-validated) questionnaires were included to comprehensively map HRQL measures and to identify whether investigator-developed questionnaires captured domains not represented by existing PROMs. Twelve of the identified PROMs were developed or subsequently validated for cancer populations. Items from each PROM were extracted and coded, identifying 62 sub-themes further organized into 6 top-level themes. Content...